Biostimulators
OVERVIEW
Stimulate your body’s natural production of collagen to improve bone density and skin quality
Biostimulators are compounds like Sculptra and Radiesse that are injected into the skin to help your body’s cells function better and regenerate tissue. They stimulate the production of elastin and collagen, proteins that keep your skin firm and elastic, encouraging your body to naturally repair and restore your skin’s structure and helping it rebuild on its own.
-
Dose-based (by syringe/vial)
-
Up to 2 years depending on treatment
-
Injection
-
SCULPTRA®, RADIESSE®(+), PDGF+
-
45 minutes
-
Within weeks, improving with increased collagen production for up to 12 months
-
When you start to see loss of volume and elasticity
TREATMENTS
FIG.03 BIOSTIMULATOR TREATMENT AREAS
Build support
Radiesse is an injectable biostimulant made with calcium hydroxylapatite (CaHA), which forms a supportive scaffold beneath the skin to stimulate collagen and elastin production. This results in smoother skin and improved structure over time, with natural-looking results that typically last around 15 months.
Stimulate collagen
Sculptra is an injectable biostimulator made with poly-L-lactic acid (PLLA) that gradually stimulates production of collagen types 1 and 3 to improve skin firmness, volume and elasticity. Treatment is typically performed as a series of up to two to four sessions, with results developing gradually and lasting up to two years.
Rejuvenate your skin
Ariessence PDGF+ uses pharmaceutical-grade Platelet-Derived Growth Factor (PDGF) to stimulate natural tissue regeneration and repair. By enhancing collagen production, cellular renewal, and microcirculation, it offers a powerful, non-surgical option for both skin and hair rejuvenation.
PRICING & Timelines
Your optimal dosing will be discussed during your Complete Assessment, where we consider factors such as facial anatomy, age, skin quality, and your personal goals to craft a plan that’s uniquely tailored for you.
Sculptra
Full syringe: $900
-
• 1 to 2 initial sessions, spaced about 4-6 weeks apart
• Followed by maintenance sessions roughly every 12 months, depending on skin goals and aging concernsThe exact number may vary based on the individual's skin condition, age, and whether PDGF is used alone or in combination with other treatments.
Radiesse
1 Vial: $900
-
• First treatment 1-2 syringes, that may be over multiple appointments.
• Come in for 6 month follow up photos/ensure no nodules & check progress
• 1 year post treatment, routine follow up for maintenance & skin quality assessment
PDGF+
$650-$850 per treatment
-
• First treatment 1 vial
• Massage the face 5x a day for 5 days (about 30-60s each time) post treatment
• Follow up in 4-6 weeks to assess body's response to treatment
• Second treatment 4-12 weeks after first vial
• 6 month follow up for photos & assessment
• 1 year from first vial appointment follow up to see about maintenance & skin quality
First-time clients: Book The Complete Assessment
•
First-time clients: Book The Complete Assessment •
the experience
What to expect during your Biostim visit
Aesthetic consultation rooted in balance
Your visit begins with a comprehensive, full-face consultation. We’ll assess what may be disrupting your natural facial ratios and design a treatment plan to help restore harmony.
Tailored treatment plan
We’ll discuss recommended dosing and treatment areas ensuring every detail aligns with your unique features and goals.
Transparent pricing
You'll receive clear, upfront pricing before treatment.
No pressure
There's absolutely no pressure to treat. You're encouraged to move forward only if and when you feel comfortable after your consultation.
Designed for comfort
A topical anesthetic can be applied before treatment for your comfort.
Minimal visibility
There may be more visibility post biostimulator treatment such as bruising and swelling. Visible signs of treatment will depend on the type of product and treatment area.
Little to no downtime
Bruising, swelling and redness can occur and can last up to 7 days. Redness can last up to 3 weeks.
POST VISIT
Aftercare for the most successful results
Restrictions
Please refrain from all exercise, facials, and massages for 48 hours post-treatment to ensure proper recovery.
Progress Check-In
We’ll follow up in two weeks to evaluate your response, monitor how your biostims are responding, and see if any additional treatments are needed.
Accessibility
You’ll have direct access to your provider for any questions, concerns, or touch-ups. Your care doesn’t end when you leave our office.
your questions, answered
-
On average, you will have 1 to 3 treatment sessions over the course of a few months. The number of injections at each session will vary based on the treatment plan determined by you and your aesthetic professional
-
Results are immediate. Results continue to improve with collagen production starting at 4-6 weeks. Optimal results are seen at 6 months up to 1 year, with sustained results for up to 2 years post treatment.
-
Post treatment you will see immediate improvement of treated areas. Most common side effects are bruising, swelling and pain to injection sites that can last up to 5-7 days post treatment.
-
• Do not workout for 24-48 hours
• If you are worried about bruising or swelling do not drink alcohol for 24 hours after treatment
• Avoid excessive sun exposure, extreme heat (i.e sauna and steam room) for 24-48 hours after treatment
-
Radiesse provides best results when used in jawline, cheekbones, temples, and hands. Radiesse can be used in most areas except for lips and under eyes. Deciding where to treat with Radiesse will be discussed with your provider during your appointment.
-
• The short answer is Yes! Radiesse cannot be injected in areas where there is minimal to no facial fat, aka the forehead, glabella, or crows feet region. You will need to keep up with those areas every 3-4 months or as needed.
• Lower face tox areas will also likely need be maintained (DAO, chin, lip flip, bunnies, masseter) and often support Radiesse treatments and results.
• Radiesse cannot be used to treat lips or under eyes, other hyaluronic acid based dermal fillers may also be utilized with Radiesse pending treatment plan and desired results.
-
You can absolutely wear makeup after your treatment! We recommend light weight mineral makeup for the first 24 hours.
-
Common adverse events observed in clinical studies of RADIESSE® include bruising, redness, swelling, pain, itching, lumps/bumps at site of injection, difficulty chewing and other local side effects. If you undergo any radiographic imaging inform your provider of previous RADIESSE® treatments as there have been cases of RADIESSE® detection on radiographic imaging. Please review patient brochure for a complete list of side effects and contraindications to treatment.
-
On average, you will have 1 to 3 treatment sessions over the course of a few months. The number of injections at each session will vary based on the treatment plan determined by you and your aesthetic professional.
-
Most clinical study participants saw results as soon as 1 month, with optimal results at 6 months - 1 year with sustained results for up to 2 years post treatment. A typical treatment plan includes 2-3 sessions spaced at least 4 to 6 weeks apart.
-
Massage the treated area to evenly distribute Sculptra for 5 days post treatment. A good rule of thumb is 5-5-5: Massage the injected area for 5 minutes, 5 times a day, for 5 days in a row.
-
• Do not workout for 24-48 hours
• If you are worried about bruising or swelling do not drink alcohol for 24 hours after treatment
• Avoid excessive sun exposure, extreme heat (i.e sauna and steam room) for 24-48 hours after treatment
-
• Sculptra is used for full facial rejuvenation from the temples down.
• Administered with the appropriate injection technique from a trained specialist, Sculptra is clinically approved for: Cheek wrinkles, Deep folds between the nose and mouth (nasolabial folds), lines framing the mouth (marionette lines), Chin wrinkles, and temples.
-
• Yes. Sculptra cannot be injected in areas where there is minimal to no facial fat, aka the forehead, glabella, or crows feet region. You will need to keep up with those areas every 3-4 months or as needed.
• Lower face tox areas will also likely need be maintained (DAO, chin, lip flip, bunnies, masseter) and often support Sculptra treatments and results.
• Sculptra cannot be used to treat lips or under eyes, other hyaluronic acid based dermal fillers may also be utilized with Sculptra pending treatment plan and desired results.
-
You can absolutely wear makeup after your treatment! We recommend light weight mineral makeup for the first 24 hours.
-
• Sculptra is FDA-approved in the United States and has been used worldwide since 1999. Sculptra is made of a synthetic material called poly-L-lactic acid that is absorbed naturally by the body and has been used for years in dissolvable stitches.
• Since Sculptra does not contain any human or animal components, no allergy testing is needed prior to treatments.
• Side effects reported include injection site pain, redness, bruising, tenderness, itching and lumps, bleeding, and swelling. Small bumps under the skin can sometimes be noticeable when pressing on the treated area. Larger lumps, with or without inflammation, have also been reported.
-
• History of anaphylaxis or multiple severe allergies
• History of autoimmune disease
• Allergies to any of the ingredients in Sculptra, including poly-L-lactic acid (PLLA), carboxymethylcellulose (USP), or non-pyrogenic mannitol (USP)
• History of or susceptible to keloid formation or hypertrophic scarring
-
PDGF+, Platelet-Derived Growth Factors, uses pure recombinant human platelet-derived growth factor-BB (rhPDGF-BB), a pharmaceutical-grade growth factor that’s identical to what your body naturally produces when healing.
-
PDGF is most commonly used for:
• Under-eye hollows and dark circles
• Fine lines and skin laxity
• Hair thinning on the scalp
• Scarring or dull skin tone -
Most patients benefit from 1 to 4 initial sessions, spaced about 4-6 weeks apart, followed by maintenance treatments as needed.
-
Some improvement may be visible within a few weeks, but optimal results typically appear after a full series of treatments, as collagen production and tissue repair take time.
-
Downtime is minimal. You may experience slight redness, swelling, or bruising at the injection site. Redness can persist for up to 3 weeks, but can be covered with makeup right after treatment.
-
PRP, or Platelet-Rich Plasma, requires a blood draw and spinning your own plasma. PDGF+ delivers much higher concentrations of growth factors without the fuss of drawing blood first.
More Growth Factors = Better Results PDGF+ delivers a higher potency than PRP. Up to 300,000x the amount of growth factor.
No Blood Draw Required - A simpler, more comfortable experience.
Predictable - Pharmaceutical-grade PDGF provides a high-quality and consistent product.
-
Anyone experiencing early signs of aging, under-eye hollowness, or hair thinning may be a good candidate. A consultation will determine if PDGF is right for your goals.
The above information attempts to define principles of risk disclosure that should generally meet the needs of most patients in most circumstances. However, this information should not be considered all inclusive in defining other methods of care and risks encountered, results and downtime can vary from patient to patient. Your Physician, Registered Nurse, and/or certified Aesthetician may provide you with additional or different information which is based on all the facts in your particular case and the state of medical knowledge.
Reduce muscle activity that can cause skin damage, wrinkles & resting lines
Restore volume loss with intentional support & structure in areas where you need it most
Stimulate your body’s natural production of collagen to improve skin quality
Restore your skin’s radiance by combating aging, damage & hyperpigmentation